Master Practitioner Workshop

We invite you to attend a special three-day workshop for practitioners in our hometown of Kansas City!  This workshop will provide in-depth information about some of our most popular and clinically useful tests, so you can better incorporate them into your practice and create better health outcomes for your patients.  Tests covered in this workshop include the Organic Acids Test, GPL-TOX (Toxic Non-Metal Chemical Profile), Glyphosate Test, GPL-SNP1000 (DNA Sequencing Profile), and more!  You will learn about key markers in the tests, why they are relevant, how to interpret results, how to use the tests in tandem, and will review possible treatment options that have been effective.  Registration for this workshop will be limited, so reserve your place now!  

The backdrop for this workshop will be one of the most iconic areas of Kansas City, the Country Club Plaza.  The Plaza is an outdoor museum of romantic Spanish architecture and European art where people actually live and work every day amid its beauty. It was designed in 1922 as the nation’s first suburban shopping district. Since then, its open-air public art gallery has continuously added to its collection, with fountains, sculptures, and murals that bring to the heart of our city the very best of the Old World and the new.  The Plaza offers fifteen blocks of possibilities, with around 50 different restaurants, and close to 100 shops.  You’ll be near Plaza area attractions like The Nelson-Atkins Museum of Art, Heart of America Shakespeare Festival (runs in the summer), and Loose Park.   Other nearby hot spots in Kansas City include Union Station, Crown Center, the National World War I Museum and Memorial,  Kauffman Center for Performing Arts, the Crossroads Arts District, and the Power & Light District.

Qualified attendees at the Organic Acids Testing Workshop receive a FREE Organic Acids Test, worth $299.00!

July 14-16, 2017  |  Kansas City, MO

A Special Three-Day Educational Event for Practitioners in the Heart of America and Home to The Great Plains Laboratory, Inc.



  • Through June 11, 2017


  • June 12 - July 9, 2017

LATE PRICING  |  $425.00

  • After July 9, 2017


  • Accreditation information can be found below.

Saturday Evening Rooftop Banquet | $35

  • Space is limited, so please reserve your spot now!


9 Continuing Medical Credits (CME/CEU)**  are provided by Westbrook University for MDs, DOs, NDs, DCs, LAcs, NPs, and PAs for a fee of $100.00.*  These credits are approved by AAFP. For more information about these credits, go to

** It is the responsibility of the attendee to adhere to the CME/CEU requirements of his/her state licensing board and to check to be sure these credits will be approved before the workshop. No refunds will be issued for CME fees. CMEs/CEUs are not APA approved.

**CME certificates are mailed directly to you by Westbrook University at the address you supplied upon registration.  Requests for replacement or additional certificates for any reason, whether by mail or e-mail will incur a fee of $15.00.

18.5 CE Credit Hours are available to RNs, provided by Commonwealth Seminars for a fee of $100.00.  Partial CE credit is not available.


The Health Implications of Microorganisms

July 14, 2017
Microorganisms are single celled organisms that includes yeast, bacteria, fungus, and mold.  The human body has over 30 trillion bacteria and yeast cells living in the digestive tract.  The bacteria belong to more than 1,000 species, mainly in the Firmicutes and Bacteroidetes families.  These bacteria have a large influence on digestive health, the immune system, metabolism, and mental health.  When these beneficial bacteria are disrupted by opportunistic pathogens such as Clostridium difficile, a number of chronic illnesses can manifest.  Not only do these pathogenic bacteria disrupt the beneficial bacteria, they also produce a number of toxins that can further disrupt normal bodily processes.  Yeast and bacteria can also be sources of oxalates.  Oxalates can crystalize in the body and lead to inflammation in many different tissues.  Another very pervasive group of microorganisms is mold, which produce metabolites called mycotoxins.  Most mold exposures come from food or spores in the home.  Many homes have undiscovered mold issues which can lead to toxic exposure.  On day one, we will cover testing and treatment options to help manage our complex microbiome, as well as the threat posed by mycotoxins.


The Health Implications of Metal & Non-Metal Toxicants

July 15, 2017
Our bodies are exposed to more toxins in our environment now than ever before.  These toxins include solvents, rubberizers, plasticizers, herbicides, pesticides, flame retardants, stain repellants, and many more.  Organophosphate pesticides and herbicides are the most commonly used chemicals in the world.   The United States uses about 100 million tons of organophosphates each year.  Organophosphate exposure can lead to mitochondrial dysfunction, neurobehavioral deterioration, and microbiome alteration, which can lead to chronic disease.  Our laboratory has developed tests for over 160 different organophosphates.  We have also developed tests to detect the popular herbicides 2,4-Dichlorophenoxyacetic acid (2, 4-D) and glyphosate.  In addition to these organic compounds, many people are being exposed to heavy metals.  The most prevalent of these include lead and mercury.  Exposure to heavy metals can lead to mental illness, fatigue, cancer, Alzheimer’s, and many other diseases.  On day two, we will cover detection of these metal and non-metal toxins and discuss treatment options.  


The Inflammatory Basis of Diseases

July 16, 2017
Using Specific Tests to Discover and Treat Chronic Inflammation
Inflammation has been implicated in many different chronic diseases and can occur in almost every tissue of the body.  Prevention and reduction of inflammation can often lead to better health outcomes.  The Great Plains Laboratory has focused on how inflammation can be managed for numerous types of chronic diseases, with a focus on mental health.   First, we developed our Phospholipase A2 Activity Test because of PLA2’s inflammatory role in many chronic diseases.   Second, we are able to monitor neurotransmitter metabolites via the Organic Acids Test.  Third, we utilize our genetic test (GPL-SNP1000) to help determine how to best treat neurotransmitter abnormalities caused by genetic mutations, pathogens, or toxins.  Our genetic test also gives insight into the methylation pathway, which is involved in inflammation support, neurotransmitter production and metabolism, and detoxification.  Finally, we provide an IgG Food Allergy Test and Gluten + Casein Peptides Test to assist in determining how diet can lead to inflammation and chronic disease.  On day three, we will review how all of these tests can be used to discover sources of inflammation in the body and brain, as well as treatments that have been effective.


William Shaw, PhD

Dr. Shaw is board certified in the fields of clinical chemistry and toxicology by the American Board of Clinical Chemistry. Before he founded The Great Plains Laboratory, Inc., Dr. Shaw worked for the Centers for Disease Control and Prevention (CDC), Children’s Mercy Hospital, University of Missouri at Kansas City School of Medicine, and Smith Kline Laboratories. He is the author of Biological Treatments for Autism and PDD, originally published in 1998 and Autism: Beyond the Basics, published in 2009. He is also a frequent speaker at conferences worldwide.


Kurt Woeller, DO

Dr. Woeller has been an integrative medicine physician and biomedical autism specialist for 15+ years.  He is the author of several books including Autism – The Road To Recovery, Methyl-B12 Therapy For Autism, Methyl-B12 for Alzheimer’s Disease and Dementia, and 5 Things You MUST Do Right Now To Help With Your Rheumatoid Arthritis.  He is a lecturer (United States and International), educator and experienced clinician offering specialized treatment and testing for individuals with complex medical conditions such as autism spectrum disorders, chronic fatigue syndrome, mental health disorders, multiple sclerosis, and other chronic health conditions.


Matthew Pratt-Hyatt, PhD

Dr. Pratt-Hyatt received his doctorate in cellular and molecular biology from the University of Michigan.  He has trained under Dr. Paul Hollenberg, a prominent researcher on drug metabolism and Dr. Curtis Klaassen, one of the world’s leading toxicologists.  He has over a dozen publications in well-known research journals such as PNAS and Cell Metabolism.  At The Great Plains Laboratory, he specializes in developing tools that examine factors at the interface between genetics and toxicology, how genes and toxicants interact, and how that may lead to mental health disorders, chronic health issues, and metabolism disorders.


Rick Sponaugle, MD

Rick Sponaugle M.D. is an integrative physician with an emphasis on environmental medicine and tick-borne infections and specializes in treating brain and neurological disorders derived from severe neurotoxicity.  He has performed analysis of 9,000 neurotransmitter patterns and 6,000 mold mycotoxin levels in neurotoxic patients.  Dr. Sponaugle has written chapters on neurotoxicity for Suzanne Summers and has been featured on the Dr. Phil show, Suzanne Somers show, CNN, FOX News, ABC News, CBS News, NBC News, and PBS.  Dr. Sponaugle is the medical director of Sponaugle Wellness Institute in Tampa Bay, Florida.


The workshop venue is The Fontaine Hotel (Formerly Hotel Sorella).  Discover a refined oasis and Kansas City’s newest destination hotel tucked amid the ornate fountains and elegant courtyards of Country Club Plaza.  The newly constructed Fontaine Hotel features a grand fusion of modern design and Mediterranean inspiration. Details playfully mirror the Plaza’s influence of Spanish Seville, such as the breathtaking rooftop pool and Renaissance-style artwork, all with a fashionable flair for the dramatic. This hotel is just steps away from the famed fountains of Country Club Plaza and all of the dining, shopping and nightlife that the Plaza has to offer.

Room Reservations

We have a small block of rooms reserved at The Fontaine  for a discounted rate of $189/night. Guests can go to and follow these steps:

  1. Enter arrival and departure dates
  2. Under “Promotional” Select: “Group/Block”
  3. Enter your group code: 0707THEGRE (You will find this under their group booking)
  4. Click “Check Availability”

You may also call our reservations line at 855.596.3399 and ask to make a
reservation under the group name: "Great Plains Laboratory Inc."

These discounted rooms will sell out fast.  Once our block is sold out, you may reserve a room at The Fontaine at the regular rate or make a reservation at one of the other hotels on the Country Club Plaza.  Please see below for a list of hotels and their distance from The Fontaine


GPL will be covering all hotel parking expenses for workshop attendees.

Airport and Transportation

Kansas City International Airport (MCI) is located 28 miles from the Country Club Plaza and The Fontaine.  For all airport transportation options, go to  For navigation purposes, enter 1 International Square, Kansas City, MO 64153 into your electronic device.

The Fontaine Hotel (Formerly Hotel Sorella)

901 W 48th Place Kansas City, MO 64112

Kansas City Country Club Plaza Hotel OPTIONS

Below is a list of additional hotels on or near the Country Club Plaza in Kansas City.

Hampton Inn and Suites Country Club Plaza
(.4 miles from The Fontaine)

The Raphael Hotel
(.6 mile from The Fontaine)

Extended Stay America Country Club Plaza
(.9 mile from The Fontaine)

Best Western Plus Seville Plaza
(1.2 mile from The Fontaine)

Sheraton Suites Country Club Plaza
(.5 mile from The Fontaine)

Intercontinental Kansas City at the Plaza
(.7 mile from The Fontaine)

Marriott Country Club Plaza
(1 mile from The Fontaine)

Residence Inn by Marriott Country Club Plaza
(.5 mile from The Fontaine)

Courtyard by Marriott Country Club Plaza
(.7 mile from The Fontaine)

Embassy Suites by Hilton Kansas City Plaza
(1.1 mile from The Fontaine)



Registration and Breakfast

Introduction To The Organic Acids Test and Why It Is So Important In Clinical Practice

Hundreds of organic acid metabolites are found in the urine of all mammals, including humans. These metabolites can be used for both diagnostic and therapeutic measurements for detecting abnormal gastrointestinal overgrowth or dysbiosis, assessing mitochondrial energy production, detecting genetic diseases, assessing malnutrition and suboptimum nutrition, revealing toxic exposure, finding alterations of neurotransmitter metabolites in neurological and psychiatric disorders, and assessing metabolites that cause severe inflammation in a variety of chronic illnesses.

The Link Between Invasive Candida and Various Health Issues

The OAT evaluates for various fungal toxins, including specific markers for Candida. Many people rely on stool testing for Candida diagnosis and miss the presence of Candida toxins through the Organic Acids Test. Candida can lead to neurochemical imbalances in the brain, as well as sensory problems and self-stimulatory behavior (often seen in autism).

The Link Between Clostridia Bacteria Toxins and Various Health Issues

The OAT evaluates for two specific toxins related to Clostridia bacteria – HPHPA and 4-cresol. Both of these toxins can inhibit a dopamine converting enzyme, leading to excess dopamine and toxic reactions in the brain and nervous system. Problems such as moodiness, irritability, aggression, self-injurious behavior, sleep difficulties, and more can be associated with Clostridia bacteria overgrowth.

Oxalate Metabolism: Risks and Treatments

Oxalate and its acidic form, oxalic acid, are formed from diet, human metabolism, and from yeast/fungal overgrowth. Oxalates are known to combine with calcium to form crystals that can cause kidney stones, as well as build up in the bones, joints, blood vessels, lungs, and even the brain. This section will review the genetic risks of impaired oxalate metabolism and recommended treatments to prevent and reverse high oxalate levels.

The Hidden Threats of Mycotoxins

Mycotoxins are some of the most prevalent toxins in the environment. Mycotoxins are metabolites produced by fungi like mold, which can infest buildings, vehicles, and foods. A majority of mycotoxin exposures are through food ingestion or airborne exposure.

Correlation of Neurological Symptoms with PET Brain Imaging In Mold Toxic Patients

This presentation will correlate neurological symptoms in mold toxic patients with their PET brain imaging. It will also elucidate two mechanisms by which mold mycotoxins down-regulate brain activity, fatty acid oxidation, and mitochondrial dysfunction.

End of Day 1 Workshop




Non-Metal Toxic Chemicals and Their Effects on Health

A huge array of non-metal toxic chemicals like phthalates, pyrethrins, organophosphates and many others can now be tested conveniently and economically in a single morning urine sample. Learn how to use this testing and apply it to a wide variety of chronic illnesses such as neurological disorders, psychiatric disorders, chronic fatigue, and many others. The best treatment options will be presented in great detail.

Glyphosate, 2,4-D, GMO Foods, and the Microbiome

The widely used weed killer glyphosate (Roundup™) has been implicated as a cause of chronic kidney disease and cancer. Exposure to glyphosate may alter the microbiome of all of our agricultural soil and seriously alter the intestinal flora of humans and farm animals. Learn how GMO foods are connected with a wide variety of other chronic illnesses because of glyphosate contamination.

Genetic Testing: The Route to Personalized Medicine

This section will provide an overview of the different types of genetic testing available and explain why Next-Generation Sequencing (NGS) is the superior form of genetic testing. It will also describe why GPL-SNP1000 is the best genetic test to use in integrative medicine, before reviewing six of the nine important pathways that it covers.

How Genetics Affects the Detoxification of Drugs and Environmental Toxicants

The environment that we live in today is the most toxic in history; in part because of the vast amounts of pharmaceutical drugs patients are being prescribed. It is important for our bodies to be able to eliminate these potentially toxic compounds. The enzymes that are critical to neutralize and eliminate them include the cytochrome P450s, the sulfur transferases, the glutathioine transferases, and the methyltransferases. This section will review mutations relevant to drug metabolism so that you may help prevent adverse drug reactions in your patients.

Case Studies: PET Brain Imaging in Patients Suffering From Severe Industrial Toxicity

This presentation will correlate the hypometabolism seen on PET brain imaging with industrial toxin levels, fatty acid oxidation biomarkers, and biomarkers for mitochondrial dysfunction.

Heavy Metals and Their Role in Chronic Health Disorders

Heavy metals like cadmium, lead, and mercury are associated with many chronic illnesses and cancer. Find out the best way to test these metals, as well as simple protocols for treatment of excessive exposures.

End of Day 2 Workshop




Neurochemical Imbalances and Quinolinic Acid Toxicity

The OAT evaluates serotonin (an important brain chemical for mood, fine and gross motor skills, and calmness), as well markers that can indicate toxic stress in the brain and nervous system, like quinolinic acid, which are important to evaluate before prescribing certain supplements, particularly L-Tryptophan, which is commonly used to help with sleep.

Case Studies with the Organic Acids Test

Methylation: How Methylation Affects Mental Health, Cardiac Health, and Detoxification

The MTHFR pathway is important for folate metabolism, which is responsible for the formation of methionine, S-Adenosyl methionine (SAMe), and thymidylate monophosphate (dTMP). These compounds play critical roles in nucleotide synthesis (making more DNA for new cells), neurotransmitter synthesis, CoQ10 production, histamine breakdown, and numerous other processes. This section will review problems that can arise from mutations in the MTHFR gene and recommended interventions.

Understanding the Risks for Developing Mental Health Disorders and Possible Interventions

Many neurological diseases are linked mutations in genes that either produce or metabolize neurotransmitters, which can predispose patients to a variety of ailments including depression, schizophrenia, anxiety, and bipolar disorder. This section will review some of the primary genes relevant to mental health, as well as correlating treatment options.

The APOE Gene: An Important Risk Factor for Alzheimer’s

One of the most important transporter proteins is APOE, also known as “The Alzheimer’s Gene”. This section will review some of the diseases associated with mutations that result in faulty transport, including Alzheimer’s Disease.

How Peptides Affect Chronic Health Issues

Peptides are small proteins that have profound effects on eating behavior, digestion, pain, immunity, infection, addiction, and more. We will review some of the most well-researched peptides such as the opiate peptides from wheat, milk, and soy.

IgG Food Allergy Testing: Scientific Evidence of its Validity in Chronic Illness

IgG food allergy has been implicated in a wide variety of illnesses including chronic fatigue, irritable bowel syndrome, obesity, autism, depression, schizophrenia, migraine headache, and many others. Learn about the different types of allergy testing and the treatments for allergies.

PLA2: The Possible Root Cause of Many Inflammatory Disorders

Phospholipase A2 (PLA2) is elevated in a variety of inflammatory conditions including multiple sclerosis, cardiovascular disease (including atherosclerosis), Crohn’s disease, neurodegenerative diseases, bipolar depression, schizophrenia, and sepsis. This section will review new information about PLA2, methods for PLA2 testing, and treatment options.

End of Day 3 Workshop