FEBRUARY 8-10, 2019


Qualified attendees that attend all three days will receive a FREE Organic Acids Test, worth $299!

Day 1

The Clinical Significance of Organic Acids Testing

Learn how to use this comprehensive metabolic test in your practice to help with your most difficult-to-diagnose patients. With 74 markers, including those for yeast and bacteria overgrowth, inflammation, oxidative stress, mitochondrial dysfunction, oxalates, gastrointestinal dysbiosis, and nutritional imbalances, the Organic Acids Test (OAT) helps you discover the underlying causes of many chronic conditions. When you attend this workshop, you will not only learn how the OAT can be used in clinical practice, but also ways to use it along with other diagnostic assessments, as well as what kinds of treatments have been effective.

Day 2

The Health Implications of Metal and Non-Metal Toxins

This workshop will focus on the epidemic of environmental toxin exposure, from the many chemicals we encounter every day, to heavy metals, to mycotoxins released from mold. You will learn about many common environmental pollutants from the 172 chemicals tested by our GPL-TOX Profile.  You will find out how these chemicals can affect our health and what steps can be taken to help detoxify the body.  You will also learn about the eleven types of mold mycotoxins tested for in our new MycoTOX Profile and about the chronic health conditions mycotoxin exposure can cause.  We will review how to use these tests in your practice to create the most effective treatments possible for your patients. 

Day 3

The Inflammatory Basis of Disease

Using Specific Tests to Discover and Treat Chronic Inflammation
Inflammation has been implicated in many different chronic diseases and can occur in almost every tissue of the body.  Prevention and reduction of inflammation can often lead to better health outcomes.  The Great Plains Laboratory has focused on how inflammation can be managed for numerous types of chronic diseases, from depression and Alzheimer’s disease, to fibromyalgia and cardiovascular disease, and this all started with the Organic Acids Test.  We then developed our Phospholipase A2 Activity Test because of PLA2’s inflammatory role in many chronic diseases.  Finally, we provide an IgG Food Allergy Test and a Gluten + Casein Peptides Test to assist in determining how diet can lead to inflammation and chronic disease.  On day three, we will review how all of these tests can be used to discover sources of inflammation in the body and brain, as well as treatments that have been effective.



organic acids testing

8:00am | Registration and Breakfast

8:45am | Introduction To The Organic Acids Test and Why It Is So Important In Clinical Practice

Hundreds of organic acid metabolites are found in the urine of all mammals, including humans. These metabolites can be used for both diagnostic and therapeutic measurements for detecting abnormal gastrointestinal overgrowth or dysbiosis, assessing mitochondrial energy production, detecting genetic diseases, assessing malnutrition and suboptimum nutrition, revealing toxic exposure, finding alterations of neurotransmitter metabolites in neurological and psychiatric disorders, and assessing metabolites that cause severe inflammation in a variety of chronic illnesses.

The OAT evaluates for various fungal toxins, including specific markers for Candida. Many people rely on stool testing for Candida diagnosis and miss the presence of Candida toxins through the Organic Acid Test. Candida can lead to neurochemical imbalances in the brain, as well as sensory problems and self-stimulatory behavior (often seen in autism).

11:15am | Morning Break

The OAT evaluates for two specific toxins related to Clostridia bacteria – HPHPA and 4-cresol. Both of these toxins can inhibit a dopamine converting enzyme, leading to excess dopamine and toxic reactions in the brain and nervous system. Problems such as moodiness, irritability, aggression, self-injurious behavior, sleep difficulties, and more can be associated with Clostridia bacteria overgrowth.

12:45pm | Lunch

The OAT includes glycolic and glyceric acids in the oxalate section, which can differentiate between genetic and nutritional components in disturbed oxalate metabolism. Oxalates are compounds found in many foods, and can be worsened by Candida overgrowth. High oxalates are associated with pain in the joints, muscles, and connective tissues. They can also trap heavy metals (such as mercury, lead, and arsenic) in the body and lead to mineral imbalances. Certain behavioral issues and self-injurious tendencies have been associated with high oxalates.

2:30pm | Neurochemical Imbalances and Quinolinic Acid Toxicity

The OAT evaluates for imbalances in serotonin (an important brain and nervous system chemical for mood, fine and gross motor skills, and calmness), as well additional markers that can indicate toxic stress in the brain and nervous system, such as quinolinic acid. High quinolinic acid suggests toxic stress in the brain and is important to evaluate before prescribing certain supplements, particularly L-Tryptophan which is commonly used to help with sleep.

3:30pm | Afternoon Break

4:00pm | Additional Case Studies: Lab Reviews and Treatment Options

This presentation will highlight various patient cases from clinical practice that show the role of biomedical intervention for various patient scenarios such as dietary therapy, yeast and Clostridia treatment, and methylation support.

Day 2

The Health Implications of Metal and Non-Metal Toxins

8:00am | Breakfast

8:40am | Non-Metal Toxic Chemicals and Their Effects on Health

A huge array of non-metal toxic chemicals like phthalates, pyrethrins, organophosphates and many others can now be tested conveniently and economically in a single morning urine sample. Learn how to use this testing and apply it to a wide variety of chronic illnesses such as neurological disorders, psychiatric disorders, chronic fatigue, and many others. The best treatment options will be presented in great detail.

10:00 am | Glyphosate, 2,4-D, GMO Foods, and the Microbiome

The widely used weed killer glyphosate (Roundup™) has been implicated as a cause of chronic kidney disease and cancer. Exposure to glyphosate may alter the microbiome of all of our agricultural soil and seriously alter the intestinal flora of humans and farm animals. Learn how GMO foods are connected with a wide variety of other chronic illnesses because of glyphosate contamination.

11:15am | Morning Break

11:45am | The Hidden Threat of Mycotoxins

This presentation will review the specific markers in the GPL-MycoTOX Profile and how you may use this test in your practice to help your patients with mold exposure.

12:45pm | Lunch

2:15pm | Effective Treatment Strategies for Toxin Exposure

Rick Sponaugle, MD
Dr. Sponaugle will present several patient cases where he had success treating symptoms of mold exposure. He will review the patients’ presenting symptoms, diagnostic results, and treatment methods used in detail.

3:45pm | Afternoon Break

4:15pm | Heavy Metals and Their Role in Chronic Health Disorders

Heavy metals like cadmium, lead, and mercury are associated with many chronic illnesses and cancer. Find out the best way to test these metals, as well as simple protocols for treatment of excessive exposures.

Day 3

The Inflammatory Basis of Disease

8:30am | Breakfast

9:00am | Food Allergy Testing: Scientific Evidence of its Validity in Chronic Illness

IgG food allergy has been implicated in a wide variety of illnesses including chronic fatigue, irritable bowel syndrome, obesity, autism, depression, schizophrenia, migraine headache, and many others. Learn about the different types of allergy testing and the treatments for allergies.

10:15am | How Peptides Influence the Brain in Autism and Mental Health Disorders

Peptides are small proteins that have profound effects on eating behavior, digestion, pain, immunity, infection, addiction, and more. We will review some of the most well-researched peptides such as the opiate peptides from wheat, milk, and soy.

10:45am | Morning Break

11:15am | PLA2: The Possible Root Cause of Many Inflammatory Disorders

Phospholipase A2 (PLA2) is elevated in a variety of inflammatory conditions including multiple sclerosis, cardiovascular disease (including atherosclerosis), Crohn’s disease, neurodegenerative diseases, bipolar depression, schizophrenia, and sepsis. This section will review new information about PLA2, methods for PLA2 testing, and treatment options.

11:45am | Fatty Acids and Cholesterol in Mental Health

Deficiencies of total cholesterol and/or omega-3 fatty acids have been implicated in a number of psychiatric diseases including autism, AD(H)D, depression, Alzheimer’s disease, bipolar depression, and road rage. The significance of testing for these fats and methods to optimize these fats to prevent or treat various illnesses will be explored in detail.

12:45pm | Lunch

1:45pm | Biochemical Factors in Alzheimer's Disease: Prevention and Treatments

Alzheimer's disease is the sixth leading cause of death in the United States. Those with Alzheimer's live an average of eight years after their symptoms become noticeable to others, but survival can range from four to 20 years, depending on age and other health conditions. In 2015, there were approximately 29.8 million people worldwide with AD. It most often begins in people over 65 years, although 4% to 5% of cases are early-onset Alzheimer's which begin before this. It affects about 6% of people 65 years and older. Recent research is focused on multifactorial causes and treatments for Alzheimer’s disease and will be reviewed including genetic factors, nutritional deficiencies, toxic exposures, and nondrug treatments.


William Shaw, PhD


William Shaw, PhD, is board certified in the fields of clinical chemistry and toxicology by the American Board of Clinical Chemistry. Before he founded The Great Plains Laboratory, Inc., Dr. Shaw worked for the Centers for Disease Control and Prevention (CDC), Children's Mercy Hospital, University of Missouri at Kansas City School of Medicine, and Smith Kline Laboratories. He is the author of Biological Treatments for Autism and PDD, originally published in 1998 and Autism: Beyond the Basics, published in 2009. He is also a frequent speaker at conferences worldwide. 

Dr. Shaw is the stepfather of a child with autism and has helped thousands of patients and medical practitioners to successfully improve the lives of people with autism, AD(H)D, Alzheimer's disease, arthritis, bipolar disorder, chronic fatigue, depression, fibromyalgia, immune deficiencies, multiple sclerosis, OCD, Parkinson's disease, seizure disorders, tic disorders, Tourette syndrome, and other serious conditions.


Kurt Woeller, DO


Kurt N. Woeller, DO has been an integrative medicine physician and biomedical autism specialist for over 20+ years. He is an author of several health books including Autism – The Road To Recovery, Methyl-B12 Therapy For Autism, Methyl-B12 for Alzheimer’s Disease and Dementia, and“5 Things You MUST Do Right Now To Help With Your Rheumatoid Arthritis. He is an international speaker, educator, and practicing clinician offering specialized interventions for individuals with complex medical conditions. His health consulting practice for autism alone is multinational with families from various countries. Dr. Woeller serves as a lab advisor for BioHealth Laboratory, as well as provides educational seminars for The Great Plains Laboratory, Inc. He is cofounder of Integrative Medicine Academy (, which is an online training academy for health practitioners learning integrative medicine.


Matthew Pratt-Hyatt, PhD


Matthew Pratt-Hyatt received his PhD in cellular and molecular biology from the University of Michigan. He has trained under Dr. Paul Hollenberg, a prominent researcher on drug metabolism and Dr. Curtis Klaassen, one of the world's leading toxicologists. He has over a dozen publications in well-known research journals such as PNAS and Cell Metabolism. At The Great Plains Laboratory, he is focused on assisting with diagnosis and treatment of mitochondrial disorders, neurological diseases, chronic immune diseases, and more. He specializes in developing tools that examine factors at the interface between genetics and toxicology. His work is bringing new insight into how genes and toxicants interact and how that may lead to mental health disorders, chronic health issues, and metabolism disorders.


Rick Sponaugle, MD

Director of Sponaugle Wellness Institute

Rick Sponaugle, MD received his medical degree from West Virginia University. He served as Chief of Anesthesiology for two different hospitals in Tampa Bay and is board certified in Addiction Medicine. Dr. Sponaugle is now an integrative physician with an emphasis on environmental medicine and tick-borne infections who specializes in treating brain and neurological disorders derived from severe neurotoxicity.  He has performed analysis of 9,000 neurotransmitter patterns and 6,000 mold mycotoxin levels in neurotoxic patients.  Dr. Sponaugle has written chapters on neurotoxicity for Suzanne Somers and has been featured on the Dr. Phil Show, Suzanne Somers Show, CNN, FOX News, ABC News, CBS News, NBC News, and PBS.  Dr. Sponaugle is the medical director of Sponaugle Wellness Institute in Tampa Bay, Florida.


St. Petersburg Marriott Clearwater

12600 Roosevelt Boulevard, North, St. Petersburg, Fl 33716

The St. Petersburg Marriott Clearwater welcomes you to Florida with an unbeatable location and a stylish, boutique feel. Whether you're here in the Pinellas Park area for work or for play, you'll love the contemporary accommodations; in-room amenities include free high-speed Internet access and ultra-plush bedding. Stop by the restaurant, The Crafted Plate, for farm-fresh American dining, or enjoy a workout in the 1,600 square-foot fitness center. Exploring during your visit is easy, as our hotel is an ideal 'gateway' to the very best in the St. Petersburg area.  Tampa Bay, Clearwater Beach, and attractions like Busch Gardens are just a few minutes away!


This hotel is located just 12 miles from Tampa International Airport (TPA) and just 2 miles from St. Petersburg-Clearwater International Airport (PIE).

  • Tampa - Airport shuttle service, on request, complimentary, Shuttle Phone: +1 727 572-7800

  • St. Petersburg Airport shuttle service, on request, complimentary, Shuttle Phone: +1 727 5727800

  • Courtesy shuttle runs from 7am to 11pm and travels to and from both Tampa International airport and St. Petersburg-Clearwater International Airport.  The shuttle also runs within a 5 mile radius of the hotel.


St. Petersburg Marriott Clearwater

12600 Roosevelt Boulevard, North, St. Petersburg, Fl 33716

Coming Soon

12600 Roosevelt Boulevard, North
St. Petersburg, FL 33716

Room rate:
A block of rooms is available for a discounted rate of $169/night through January 25, 2019. 
To reserve a room by phone, call the reservations line at 727-572-7800.  Ask for the "2019 GPL Academy Workshop".  
To reserve a room online, Click Here.  



Registration is refundable, minus a $50 processing fee, if your cancellation is received in writing no later than two weeks prior to the workshop date. Attendee substitutions are allowed, but notification must be made within two weeks prior to the workshop date. After this date, under no circumstances will refunds, credits, or substitutions be granted. No refunds or credits will be given to "no shows."